Nutridom EZ Night 60 Vcaps

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  • Traditionally) used in Herbal Medicine as a sleep aid (during times of mental stress).
  • (Traditionally) used in Herbal Medicine to help relieve restlessness and/or nervousness (nervine/calmative).
  • Helps to temporarily promote relaxation.
  • Used as a sleep aid/to help promote sleep.
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Description

The triple action of EZ Night for healthy sleep care

Nervine action – Damiana

  • Soothe nervousness
  • Promote cognitive function
  • Reduce overthinking
  • Relieve restlessness

Sedative action – Passionfilwer, Lemon balm,  L-5-HTP,  Valerian

  • Promote relaxation
  • Boost sleepiness
  • Reduce insomnia
  • Enhance calmness

Relaxation action – GABA ( gamma-Aminobutyric acid),  L-Theanine  

  • Release tension
  • Reduce stress
  • Decrease anxiety
  • Improve mood

Key functions of Medicinal Ingredients of EZ Night

  1. Damiana (Turnera diffusa) (1)
  • Anxiety and depression alleviation: have potential anxiolytic effects
  • Cognitive function aid: promote relaxation and support sleep
  1. Passionflower (Passiflora incarnata) (2)
  • Relaxation and anxiety reduction: interact with GABA (gamma-Aminobutyric acid)
  • Sedative effects: relative to calming properties for anxiety and insomnia
  1. Lemon balm (Melissa officinalis) (3)
  • Antioxidant (rosmarinic acid) properties: protect cell from free radicals
  • Mood boost: reduce anxiety, stress, and depressing

 

  1. L-5-HTP (5-Hydroxy-L-tryptophan) (4)
  • Increase serotonin levels: relate to serotonin production as a precursor
  • Sleep regulation and quality: regulate sleep patterns and quality
  1. Valerian (Valeriana officinalis) (5)
  • Valerenic acid: key components of its volatile oil and have sedative properties
  • Sleep aid: improve sleep quality and reduce sleep disturbance
  1. GABA (gamma-Aminobutyric acid) (6)
  • Transmitter regulation: maintain transmitter function and neuronal excitability
  • Anxiety and stress reduction: alleviate feelings of fear, worry, and tension
  1. L-Theanine (Camellia sinensis) (7)
  • Mood enhancement: modulate the production of dopamine, serotonin, and GABA
  • Anti-anxiety properties: decrease the tension-anxiety via the neuron control

REFERENCES

  1. Szewczyk, K., & Zidorn, C. (2014). Ethnobotany, phytochemistry, and bioactivity of the genus Turnera (Passifloraceae) with a focus on damiana—Turnera diffusa. Journal of Ethnopharmacology, 152(3), 424–443.
  2. Savage, K., Firth, J., Stough, C., & Sarris, J. (2018). GABA‐modulating phytomedicines for anxiety: A systematic review of preclinical and clinical evidence. Phytotherapy Research, 32(1), 3–18.
  3. Caleja, C., Barros, L., Barreira, J. C. M., Ciric, A., Sokovic, M., Calhelha, R. C., Beatriz, M., Oliveira, P. P., & Ferreira, I. C. F. R. (2018). Suitability of lemon balm (Melissa officinalis L.) extract rich in rosmarinic acid as a potential enhancer of functional properties in cupcakes. Food Chemistry, 250, 67–74
  4. Birdsall, T. C. (1998). 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Alternative Medicine Review, 3(4), 271–280.
  5. Pyle, B. W., Tran, H. T., Pickel, B., Haslam, T. M., Gao, Z., MacNevin, G., Vederas, J. C., Kim, S. U., & Ro, D. K. (2012). Enzymatic synthesis of valerena‐4,7(11)‐diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis). The FEBS Journal, 279(17), 3136–3146.
  6. Hepsomali, P., Groeger, J. A., Nishihira, J., & Scholey, A. (2020). Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review. Frontiers in Neuroscience, 14, 923–923.
  7. Kim, S., Jo, K., Hong, K.-B., Han, S. H., & Suh, H. J. (2019). GABA and L-theanine mixture decreases sleep latency and improves NREM sleep. Pharmaceutical Biology, 57(1), 64–72.

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